Nano Diamond "Thermometer"

Nano Diamond "Thermometer" Nanodiamonds can be used in quantum computers to process quantum information, and researchers at Harvard use the quantum effects of nanodiamonds to turn them into “thermometers” that measure the temperature changes inside human embryonic stem cells. Accuracy is the state of the art. 10 times. By adding gold nanoparticles, researchers can also use lasers to heat and even kill cells in specific parts of the cell, which is expected to provide a new way to treat cancer without damaging healthy tissue, as well as new ways to study cell behavior. Research papers were published this week in the journal Nature.

In this latest study, researchers used nanowires to inject diamond crystals with a diameter of about 100 nanometers into a human embryonic stem cell, and then irradiated the cells with a green laser so that nitrogen impurities emit red fluorescence. When the intracellular local temperature changes, the intensity of red fluorescence will be affected. By measuring the intensity of the fluorescence, the temperature of the corresponding nanodiamond can be calculated. Because the diamond has good thermal conductivity, it can show the immediate temperature of the cell's internal environment like a thermometer.

The researchers also injected gold nanoparticles into the cells, and then used lasers to heat different parts of the cells. The choice of the heating point and the temperature increase were precisely controlled by the nanodiamond "thermometer." "Now we have a tool that can control temperature at the cellular level, allowing us to study the biological system's response to temperature changes," said Peter Maurer, a physicist at Harvard who participated in the study.

He pointed out that many biological processes involved in basic biology, from gene expression to cell metabolism, will be strongly influenced by temperature, nano-diamond "thermometer" will be a useful tool. For example, by controlling the local temperature of nematodes, biologists can understand the development of simple organisms. "You can heat a single cell and study whether the cells around it will slow or accelerate their reproduction," Maurer said.

There are also other methods for measuring cell temperature, such as the use of fluorescent proteins or carbon nanotubes, but these measurement methods are deficient in sensitivity and accuracy, because some of the components react with substances in cells. Maurer said that their nanometer-diamond "thermometers" have at least a 10x increase in sensitivity and can detect temperature fluctuations as fine as 0.05. And there is room for improvement because the sensitivity of the "thermometer" has reached a temperature fluctuation of 0.0018 on the outside of living cells.

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Located in the "Town of coal and machinery" (east of Beishou Road, North Dayu Street, Yanzhou District, Jining City, Shandong), Shandong Dafeng Machinery Co., Ltd. (hereinafter referred to as the "Company") is a manufacturer of agricultural machinery that integrates R&D, manufacturing, sale and service activities. Since 1995, the Company has 20-year history of developing and manufacturing agricultural machines and witnessed the startup and growth of China harvester market.
The Company's R&D and manufacturing focus on the corn segment. Its leading products include Gold Dafeng three-row self-propelled corn harvesters and Gold Dafeng four-row self-propelled corn harvesters, which all passed national promotion appraisal and enrolled into the list of promoted products. Meanwhile, its new generation Gold Dafeng corn harvesters have been developed and tested and ready to go on sale.
Employing more than 600 people, the Company is composed of manufacturing department, marketing department, engineering department, purchase department, process equipment department, QA department, HR department, administrative department, financial department, etc. The Company totally covers 100,000m2. Till now, the phase I and phase II, which include a 33,600m2 modern standard plant building and a 1,500m2 office building, have been completed, and their total investment was more than RMB 180 million.
The Company is very strong in high-efficiency Corn Harvester development and manufacturing. Now it has 160 sets of production equipment including advanced CNC laser cutter, CNC plasma cutter, 3D cutting robot, fully automatic flat line, welding robot, electrophoresis and vanish baking equipment and flexible assembly line, and 200 sets of test equipment such as 3D coordinate measuring instrument, dynamic balancing machine, ultrasonic flaw detector, physical and chemical lab, infrared thermometer, paint film thickness gauge, etc. In addition to these instruments, it also has a great variety of detecting means. The high R&D, production and detection strengths together ensure that the Company's high-efficiency corn harvesters are highly precise, reliable and efficient.
Always operating in line with the honest and win-win philosophy, the Company formed good partnership with its suppliers and dealers, which in turn strengthens and stabilizes its supply and completing system. Now, its supplier number is 160, of which more than 110 are professional manufacturers with high production capacity. Its sales and after-sales service networks covers all major corn production areas in China, such as Shandong, Henan, Anhui, Shanxi, Shaanxi, Hebei, Jiangsu, Inner Mongolia, Heilongjiang, Jilin and Liaoning.
In future, the Company, still following the "Grateful, Honest, Efficient, Partnership-Oriented, Innovative and Responsible" concept, will continue to focus on developing and manufacturing high-efficiency corn harvesters and strive to bring its sales to more than RMB 5 billion within the coming 5 years. Aiming at becoming the top-class professional corn harvester manufacturer in China, the Company is endeavoring to build gold quality and make great contribution to agricultural modernization. Welcome to join us for great success and bright future.

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